Despite years of research, Migraine remains an incurable disease – no treatment can render sufferers permanently headache-free.
People with migraines can manage their condition by avoiding things that trigger migraines. Identifying these factors and working to make small lifestyle changes such as stress relief and better sleep habits can help prevent symptoms.
Prompt action and timely treatment helps patients get back to normal, reducing the need for painkillers.
That said, there are medications that help prevent or stop migraines, preventing the symptoms from getting worse. Panadol Migraine is one such drug.
What is Panadol Migraine?
Panadol Migraine is used to treat migraines. It belongs to a class of drugs called triptans, and helps relieve headaches, irritability, and other headache symptoms caused by nausea, vomiting, and light/sound sensitivity.
It affects a naturally occurring hormone (serotonin) that causes blood vessels in the brain to narrow. It can also relieve pain by affecting nerve cells in the brain.
Understanding migraine & its effects on the brain
Migraine is a chronic psychiatric disorder characterized by recurrent headaches ranging from moderate to severe, often associated with a number of neurologic symptoms.
Approximately 15% of the world’s population experiences migraine at some point in their lives. In chronic migraine, the patient will have cognitive symptoms associated with cerebral palsy or with symptoms of dementia on both sides of the body. Common effects of this migraine include dizziness, light-headedness, and confusion. Nausea is present in about 90% of cases, with vomiting in about a third.
Other symptoms may include blurred vision, stuffy nose, diarrhea, frequent urination, skin rash or fever. Additionally, swelling or tenderness of the scalp can occur along with back problems. Often the pin and needle sensation begins unilaterally in the hand and wrist and extends to the nostril area unilaterally. Stroke usually occurs after a previous stroke, with uncertainty about its position.
Since Panadol Migraine is an Oral Thin Film (also known as Orally Dissolving Film), it becomes much more convenient for the patient to take the required dose despite such severe symptoms. It is also very easy to apply and does not need water, unlike a heavy oral hack – a patient can put this film in their mouth anywhere, whenever they are dealing with symptoms and immediately switches to initiate action.
What are Oral Thin Films?
With recent research and technological advances, oral dosage forms have been introduced, primarily to aid in the administration of medications in children, the elderly, bed-ridden patients, constipation, . or non-compliant. Various dosage forms of mucosal bioadhesive have been developed, including tablets, gels, ointments, patches, and most recently – Oral Thin Films (OTFs). Thin film in the mouth is divided into opening film/fast degradation film, intraoral film, and sublingual film.
Open-ended film is also called fast-twitch film, fast-twitch film, and fast-twitch film.
It consists of a rapidly dissolving polymer film, incorporating a drug that is rapidly hydrated and degraded when placed on the tongue for rapid local or systemic drug delivery without the need for water a the.
The fast-degrading film melts or degrades rapidly in the mouth, resulting in solution or suspension without the use of water – in a matter of seconds.
In contrast to other existing, fast-dissolving solvents (which are composed of lyophilic materials), fast films can be produced with a manufacturing process that can compete with the solvent old manufacturing costs.
Why thin films on the edge?
The thin film in the mouth disintegrates rapidly in the mouth and ensures accurate dosing in a safe, portable, convenient and portable manner without water or dose measurement do. In addition, the thin intraoral film allows penetration into the oral cavity, thus bypassing first-pass effects in some cases.
Rizatriptan versus Sumatriptan
Panadol Migraine and sumatriptan as selective 5-HT(1B/1D) receptor agonists in the acute treatment of migraine. For oral formulations, the time to peak plasma concentrations may be earlier with Panadol Migraine than with Sumatriptan (1 h vs. 2-2.5 h) and Rizatriptan has a higher bioavailability to than Sumatriptan (45% vs. 15%).
These therapeutic advantages contribute to a faster onset of action and a better overall response to oral Rizatriptan compared to oral Sumatriptan. The two drugs have been directly compared in randomized, double-blind, placebo-controlled clinical trials with patients with moderate-to-severe migraine.
Panadol Migraine in pakistan was generally superior to Sumatriptan on the measure of pain relief time at 2 h where pain relief was defined as reduction in pain to mild or no pain (odds ratio for Rizatriptan versus Sumatriptan 100). mg = 1.21; odds ratios for Rizatriptan 10 mg versus Sumatriptan 50 mg = 1.14 and 1.10 in two trials).
The International Migraine Association reported endpoints in the percentage of patients pain-free at 2 h (40% with Rizatriptan 10 mg, 33% with Sumatriptan 100 mg, and 35% with Sumatriptan 50 mg). Other advantages for Rizatriptan were found on crude outcome measures, which included the percentage of patients who were completely free of all symptoms at 2 h, patient satisfaction with treatment at 2 h, and pain-free at 24 h.
About ZIM Laboratories
Herbal Medicos Labs is an innovative drug delivery system focused on improving patient convenience and medication adherence. We offer comprehensive solutions based on state-of-the-art technology and unrestricted manufacturing processes to develop and deliver innovative and differentiated products to our customers worldwide. At ZIM Labs we help our customers provide us with highly valued, differentiated, state-of-the-art products which can be used as a reference point. These include granules, pellets (long-lasting, modifiable, extended-release), flavoring powders, suspensions, tablets, capsules, and more recently developed Oral Thin Films (OTF).
Panadol migraine price in pakistan is around 2500 to 30000/- on Herbalmedicos.com online pharmacy so now book your order online and get free delivery to all over pakistan.